|
|
(E)-2-methylpropanal-oxime <=> Isobutyraldoxime
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
| |
BRENDA:
BR51944
KEGG:
R10034
MetaCyc:
RXN-5066
|
|
|
|
L-asparagine <=> H+ + H2O + Beta-cyanoalanine
|
3.5.5.4
cyanoalanine nitrilase
4.2.1.65
3-cyanoalanine hydratase
|
–
–
|
| |
BRENDA:
BR441
KEGG:
R01267
MetaCyc:
3-CYANOALANINE-HYDRATASE-RXN
SABIO-RK:
1484
|
|
|
|
ATP + L-aspartate + NH3 <=> diphosphate + AMP + L-asparagine + H+
|
6.3.1.1
aspartate---ammonia ligase
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
|
–
–
|
| |
BRENDA:
BR93
KEGG:
R00483
MetaCyc:
ASNSYNA-RXN
|
|
|
|
(R)-mandelonitrile <=> cyanide + benzaldehyde
|
4.1.2.10
(R)-mandelonitrile lyase
4.1.2.11
hydroxymandelonitrile lyase
4.1.2.46
aliphatic (R)-hydroxynitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
4.1.2.B6
|
–
–
–
–
–
|
| |
BRENDA:
BR6436;
BS368134
KEGG:
R01767
MetaCyc:
MANDELONITRILE-LYASE-RXN
SABIO-RK:
15344;
1865
|
|
|
|
(Z)-2-methylbutanal_oxime <=> 2-methylbutyronitrile + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
| |
BRENDA:
BR51941
KEGG:
R11639
|
|
|
|
N-hydroxy-L-phenylalanine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
| |
BRENDA:
BR49591
KEGG:
R09580
|
|
|
|
(E)-phenylacetaldoxime <=> (Z)-phenylacetaldoxime
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
|
–
|
| |
BRENDA:
BR52033
KEGG:
R10041
MetaCyc:
RXN-12065
|
|
|
|
prunasin + H2O <=> (R)-mandelonitrile + D-glucose
|
3.2.1.118
prunasin beta-glucosidase
3.2.1.119
vicianin beta-glucosidase
3.2.1.21
beta-glucosidase
3.2.1.74
glucan 1,4-beta-glucosidase
|
–
–
–
–
|
| |
BRENDA:
BR48183;
BS94662
KEGG:
R02558
MetaCyc:
PRUNASIN-BETA-GLUCOSIDASE-RXN
SABIO-RK:
2471
|
|
|
|
Dhurrin + H2O <=> (S)-4-hydroxymandelonitrile + D-glucose
|
3.2.1
3.2.1.21
beta-glucosidase
|
–
–
|
| |
BRENDA:
BS380588;
BS447425
KEGG:
R10035
MetaCyc:
RXN-9588
SABIO-RK:
13111
|
|
|
|
phenylacetonitrile + reduced_flavodoxin + O2 <=> (R)-mandelonitrile + flavin + H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
1.14.14.77
phenylacetonitrile alpha-monooxygenase
|
–
–
|
| |
BRENDA:
BR52035
KEGG:
R11733
|
|
|
|
(1E,2S)-2-methylbutanal_oxime <=> (Z)-2-methylbutanal_oxime
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
| |
BRENDA:
BR51940
KEGG:
R10030
MetaCyc:
RXN-9640
|
|
|
|
(S)-4-hydroxymandelonitrile <=> 4-hydroxybenzaldehyde + cyanide
|
4.1.2.11
hydroxymandelonitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
|
–
–
|
| |
BRENDA:
BR342
KEGG:
R02676
MetaCyc:
HYDROXYMANDELONITRILE-LYASE-RXN
|
|
|
|
Isobutyraldoxime + NADPH + H+ + O2 <=> acetone_cyanohydrin + NADP+ + 2 H2O
|
not assigned
|
–
|
| |
KEGG:
R10038
|
|
|
|
UDP-glucose + prunasin <=> amygdalin + UDP + H+
|
2.4.1
|
–
|
| |
KEGG:
R10639
MetaCyc:
RXN-18094
|
|
|
|
N,N-dihydroxy-L-tyrosine + H+ <=> p-hydroxyphenylacetaldoxime + CO2 + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
| |
BRENDA:
BR47357
KEGG:
R07190
MetaCyc:
RXN-7749
|
|
|
|
N,N-dihydroxy-L-phenylalanine + H+ <=> (E)-phenylacetaldoxime + CO2 + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
| |
BRENDA:
BR49592
KEGG:
R09581
MetaCyc:
RXN-12068
|
|
|
|
L-isoleucine + reduced_flavodoxin + O2 <=> N-hydroxy-L-isoleucine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
| |
BRENDA:
BR49377
KEGG:
R10027
|
|
|
|
cyanide + 2 H2O <=> NH3 + formate
|
3.5.5
|
–
|
| |
KEGG:
R00152
|
|
|
|
UDP-glucose + acetone_cyanohydrin <=> H+ + linamarin + UDP
|
2.4.1.63
linamarin synthase
|
–
|
| |
BRENDA:
BR44240
KEGG:
R03625
MetaCyc:
LINAMARIN-SYNTHASE-RXN
|
|
|
|
(Z)-2-methylbutanal_oxime + NADPH + H+ + O2 <=> (2R)-2-hydroxy-2-methylbutanenitrile + NADP+ + 2 H2O
|
not assigned
|
–
|
| |
KEGG:
R10036
|
|
|
|
glycine + acceptor <=> cyanide + CO2 + reduced_acceptor
|
1.4.99.5
glycine dehydrogenase (cyanide-forming)
|
–
|
| |
BRENDA:
BR36887
KEGG:
R00374;
R05704
MetaCyc:
1.4.99.5-RXN
|
|
|
|
H+ + N,N-dihydroxy-L-isoleucine <=> (1E,2S)-2-methylbutanal_oxime + CO2 + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
| |
BRENDA:
BR49379
KEGG:
R10029
MetaCyc:
RXN-9639
|
|
|
|
gamma-Amino-gamma-cyanobutanoate + 2 H2O <=> L-glutamate + NH3
|
3.5.5.1
nitrilase
|
–
|
| |
KEGG:
R01887
|
|
|
|
Isobutyronitrile + reduced_flavodoxin + O2 <=> acetone_cyanohydrin + flavin + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
| |
BRENDA:
BR51946
KEGG:
R11642
|
|
|
|
L-phenylalanine + reduced_flavodoxin + O2 <=> N-hydroxy-L-phenylalanine + flavin + H2O
|
1.14.14.40
phenylalanine N-monooxygenase
|
–
|
| |
BRENDA:
BR49590
KEGG:
R09579
|
|
|
|
lotaustralin + H2O <=> (2R)-2-hydroxy-2-methylbutanenitrile + D-glucose
|
3.2.1.21
beta-glucosidase
|
–
|
| |
BRENDA:
BS423804
KEGG:
R10039
MetaCyc:
RXN-9674
|
|
|
|
H+ + H2O + Beta-cyanoalanine <=> NH3 + L-aspartate
|
3.5.5.4
cyanoalanine nitrilase
|
–
|
| |
BRENDA:
BR48303
KEGG:
R00486
MetaCyc:
3.5.5.4-RXN
SABIO-RK:
918
|
|
|
|
2-Aminopropionitrile + H2O <=> DL-alanine + NH3
|
3.5.5.1
nitrilase
|
–
|
| |
BRENDA:
BS141170
KEGG:
R03542
|
|
|
|
(Z)-phenylacetaldoxime <=> phenylacetonitrile + H2O
|
1.14.14.44
phenylacetaldehyde oxime monooxygenase
4.99.1.5
aliphatic aldoxime dehydratase
4.99.1.7
phenylacetaldoxime dehydratase
|
–
–
–
|
| |
BRENDA:
BR48646
KEGG:
R07638
MetaCyc:
4.99.1.7-RXN
SABIO-RK:
6866
|
|
|
|
N-hydroxy-L-tyrosine + O2 + reduced_flavodoxin <=> N,N-dihydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
| |
BRENDA:
BR47356
KEGG:
R04460
|
|
|
|
L-serine + tetrahydrofolate <=> glycine + 5,10-methylenetetrahydrofolate + H2O
|
2.1.2.1
glycine hydroxymethyltransferase
|
–
|
| |
BRENDA:
BR40573
KEGG:
R00945
MetaCyc:
GLYOHMETRANS-RXN
SABIO-RK:
95
|
|
|
|
(2R)-2-hydroxy-2-methylbutanenitrile <=> cyanide + 2-butanone
|
4.1.2.10
(R)-mandelonitrile lyase
4.1.2.46
aliphatic (R)-hydroxynitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
|
–
–
–
|
| |
BRENDA:
BR49335;
BS1786;
BS406962
KEGG:
R09358
MetaCyc:
RXN-11733
|
|
|
|
L-valine + reduced_flavodoxin + O2 <=> N-hydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
| |
BRENDA:
BR49381
KEGG:
R10031
|
|
|
|
2-methylbutyronitrile + reduced_flavodoxin + O2 <=> 2-Methyl-2-hydroxybutyronitrile + flavin + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
| |
BRENDA:
BR51942
KEGG:
R11640
|
|
|
|
N,N-dihydroxy-L-valine + H+ <=> (E)-2-methylpropanal-oxime + CO2 + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
| |
BRENDA:
BR49383
KEGG:
R10033
MetaCyc:
RXN-5065
|
|
|
|
N-hydroxy-L-isoleucine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-isoleucine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
| |
BRENDA:
BR49378
KEGG:
R10028
|
|
|
|
Formamide + H2O <=> formate + NH3
|
3.5.1.49
formamidase
3.5.1.56
N,N-dimethylformamidase
|
–
–
|
| |
BRENDA:
BR22693
KEGG:
R00524
MetaCyc:
FORMAMIDASE-RXN
|
|
|
|
linamarin + H2O <=> acetone_cyanohydrin + D-glucose
|
3.2.1.117
amygdalin beta-glucosidase
3.2.1.21
beta-glucosidase
|
–
–
|
| |
BRENDA:
BS361131
KEGG:
R10040
MetaCyc:
RXN-5341
|
|
|
|
p-hydroxyphenylacetaldoxime + reduced_flavodoxin + O2 <=> (S)-4-hydroxymandelonitrile + flavin + 2 H2O
|
1.14.14.37
4-hydroxyphenylacetaldehyde oxime monooxygenase
|
–
|
| |
BRENDA:
BR29144
KEGG:
R05728
|
|
|
|
Beta-cyanoalanine <=> beta-aminopropionitrile + CO2
|
4.1.1
|
–
|
| |
KEGG:
R06614
|
|
|
|
Beta-cyanoalanine + L-glutamate <=> gamma-L-Glu-beta-cyano-L-alanine + H2O
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
| |
KEGG:
R03970
|
|
|
|
Formamide <=> cyanide + H2O
|
4.2.1.66
cyanide hydratase
4.2.1.84
nitrile hydratase
|
–
–
|
| |
BRENDA:
BR3402
KEGG:
R01408
MetaCyc:
CYANIDE-HYDRATASE-RXN
|
|
|
|
amygdalin + H2O <=> prunasin + D-glucose
|
3.2.1.117
amygdalin beta-glucosidase
3.2.1.21
beta-glucosidase
|
–
–
|
| |
BRENDA:
BR48182
KEGG:
R02985
MetaCyc:
AMYGDALIN-BETA-GLUCOSIDASE-RXN
SABIO-RK:
2837
|
|
|
|
Isobutyraldoxime <=> Isobutyronitrile + H2O
|
1.14.14.41
(E)-2-methylbutanal oxime monooxygenase
|
–
|
| |
BRENDA:
BR51945
KEGG:
R11641
MetaCyc:
RXN-5081
|
|
|
|
L-tyrosine + O2 + reduced_flavodoxin <=> N-hydroxy-L-tyrosine + flavin + H2O
|
1.14.14.36
tyrosine N-monooxygenase
|
–
|
| |
BRENDA:
BR36762
KEGG:
R00730
|
|
|
|
beta-aminopropionitrile + L-glutamate <=> gamma-Glutamyl-beta-aminopropiononitrile + H2O
|
2.3.2.2
gamma-glutamyltransferase
|
–
|
| |
KEGG:
R03971
|
|
|
|
UDP-glucose + 2-Methyl-2-hydroxybutyronitrile <=> lotaustralin + UDP + H+
|
2.4.1.63
linamarin synthase
|
–
|
| |
KEGG:
R10037
MetaCyc:
RXN-9643
|
|
|
|
UDP-glucose + (S)-4-hydroxymandelonitrile <=> H+ + UDP + Dhurrin
|
2.4.1.85
cyanohydrin beta-glucosyltransferase
|
–
|
| |
BRENDA:
BR44255
KEGG:
R04296
MetaCyc:
RXN-743
|
|
|
|
acetone_cyanohydrin <=> cyanide + acetone
|
4.1.2.37
hydroxynitrilase
4.1.2.46
aliphatic (R)-hydroxynitrile lyase
4.1.2.47
(S)-hydroxynitrile lyase
|
–
–
–
|
| |
BRENDA:
BR368
KEGG:
R01553
MetaCyc:
ACETONE-CYANHYDRIN-LYASE-RXN
SABIO-RK:
1710
|
|
|
|
UDP-glucose + (R)-mandelonitrile <=> prunasin + UDP + H+
|
2.4.1.178
hydroxymandelonitrile glucosyltransferase
2.4.1.354
(R)-mandelonitrile beta-glucosyltransferase
2.4.1.85
cyanohydrin beta-glucosyltransferase
|
–
–
–
|
| |
BRENDA:
BR52384;
BS356146
KEGG:
R10638
MetaCyc:
RXN-18095
|
|
|
|
L-asparagine + H2O <=> L-aspartate + NH3
|
3.4.11.17
tryptophanyl aminopeptidase
3.4.19.5
beta-aspartyl-peptidase
3.5.1.1
asparaginase
3.5.1.13
aryl-acylamidase
3.5.1.2
glutaminase
3.5.1.26
N4-(beta-N-acetylglucosaminyl)-L-asparaginase
3.5.1.3
omega-amidase
3.5.1.38
glutamin-(asparagin-)ase
3.5.5.4
cyanoalanine nitrilase
|
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR22679
KEGG:
R00485
MetaCyc:
ASPARAGHYD-RXN
SABIO-RK:
917
|
|
|
|
L-cysteine + cyanide <=> H+ + Sulfide + Beta-cyanoalanine
|
2.5.1.47
cysteine synthase
2.8.1.1
thiosulfate sulfurtransferase
4.4.1.9
L-3-cyanoalanine synthase
|
–
–
–
|
| |
BRENDA:
BR3447
KEGG:
R02846;
R03524
MetaCyc:
L-3-CYANOALANINE-SYNTHASE-RXN
SABIO-RK:
3312;
8566
|
|
|
|
succinate_semialdehyde + cyanide + NH3 <=> gamma-Amino-gamma-cyanobutanoate + H2O
|
not assigned
|
–
|
| |
KEGG:
R01650
|
|
|
|
cyanide + acetaldehyde + NH3 <=> 2-Aminopropionitrile + H2O
|
not assigned
|
–
|
| |
KEGG:
R01410
|
|
|
|
N-hydroxy-L-valine + reduced_flavodoxin + O2 <=> N,N-dihydroxy-L-valine + flavin + H2O
|
1.14.14.38
valine N-monooxygenase
1.14.14.39
isoleucine N-monooxygenase
|
–
–
|
| |
BRENDA:
BR49382
KEGG:
R10032
|
|
